摘要:and he is also the deputy of the Center Of Super-Diamond and Advanced Films (COSDAF). His research focuses on thin films, semiconducting nanomaterials, surface science and modification, and ions/materials interactions. He received the Japan Society of Applied Physics (JSAP) Best Paper Award in 2002, the Friedrich Wilhem Bessel Research Award of Alexander von Humboldt Foundation, Germany, in 2003, and the Outstanding Research Award of CityU in 2015. Prof. Zhang is also the Visiting Professor in Siegen University, Germany, Cuiying Guest Professor (萃英讲席教授) in Lanzhou University, Guest Professors in National Chiao Tung University, Soochow University, Hefei University of Technology, Technical Institute of Physics and Chemistry (CAS), and Shenzhen Institute of Advanced Technology (CAS). Till now he has published over 340 peer-reviewed journal papers.。The outstanding properties of diamond make it an excellent material for various device applications. Recently, diamond-based electrochemical and biomedical sensors have attracted increasing research interests. It is known that the potential applications of materials depend not only on their intrinsic properties, but also on the surface geometries in which they appear. The extreme properties of diamond, however, make it difficult to be structured to a desired geometry. This presentation will review the recent progresses in growth and nano-/micro-structuring techniques of diamond, in particular a simple and applicable method developed by us to nanostructure diamond (ranging from microcrystalline to nanocrystalline) surfaces using bias-assisted reactive ion etching (RIE) in hydrogen/argon plasmas. Various diamond nanocone/nanopillar/ nanowhisker (nanowire) arrays with high uniformity and tunable density have been achieved by using this method. The effects of initial film structure, surface roughness and RIE conditions on the size, density and geometry of nanostructures are revealed. Surface nanostructuring of diamond films is demonstrated to be an effective approach to extend and/or enhance the properties of diamond with respect to its bulk and film counterparts. Example applications of the diamond nanostructures in field electron emission, electrode, and in situ probing and drug delivery at cell level are also discussed.。

中南大学化学化工学院化语轩第四期学术交流会

讲座信息

报告题目:Nanoparticles of Fluorescent and Photovoltaic Moleculesfor Biomedical Applications

报告人Chun-Sing LEE (李振声)讲席教授

邀请人蓝敏焕

时间2019年5月14日(周二)

下午14:30-15:10

地点中南大学新校区化学楼133多功能报告厅

主讲人简介

Prof Chun-Sing Lee obtained his BSc and PhD degrees from the University of Hong Kong in 1987 and 1991 respectively. He then furthered his research career in the University of Birmingham of UK with the support from a Croucher Foundation Fellowship. He joined the faculty of the City University of Hong Kong in 1994 and is currently a Chair Professor of Materials Chemistry and the Head of the Chemistry Department. He also co-founded the Center Of Super-Diamond and Advanced Films (COSDAF) in 1998 and is now the Center’s Director. Prof Lee’s current research interests include organic electronics devices and nanomaterials for energy, environmental and biomedical applications. In 2016, he established the journal Materials Today Energy with Elsevier and serves as the Editor-in-Chief.

报告摘要

Semiconducting molecules often have interesting optical properties suitable for biomedical applications. However, they typically have poor water solubilities and are thus often overlooked. In this talk, a summary will be given on how the solubility issue can be addressed by packaging the hydrophobic molecules into nanoparticles. In particular, a newly developed approach of using ice as a template for controlling self-assembly of molecules into nanoparticles will be introduced. Examples will then be given on applications of these nanoparticles for imaging, photodynamic therapy (PDT) and photothermal therapy (PTT).

讲座信息

报告题目Diamond Film Surface Nanostructures: Morphology Control, Formation Mechanism, and Applications

报告人张文军 讲席教授

邀请人蓝敏焕

时间2019年5月14日(周二

下午15:10-15:50

地点中南大学新校区化学楼133多功能报告厅

主讲人简介

Wenjun Zhang obtained his Doctor of Philosophy degree in 1994 from Lanzhou University. He was a postdoc at the Fraunhofer Institute for Surface Engineering and Thin Films (1995 to 1997) and at the City University of Hong Kong (1997 to 1998). From 1998 to 2000, he worked as a Science and Technology Agency Fellow at National Institute for Research in Inorganic Materials. He joined CityU in 2000 again as a Senior Research Fellow. He is currently a Chair Professor in Department of Materials Science and Engineering; and he is also the deputy of the Center Of Super-Diamond and Advanced Films (COSDAF). His research focuses on thin films, semiconducting nanomaterials, surface science and modification, and ions/materials interactions. He received the Japan Society of Applied Physics (JSAP) Best Paper Award in 2002, the Friedrich Wilhem Bessel Research Award of Alexander von Humboldt Foundation, Germany, in 2003, and the Outstanding Research Award of CityU in 2015. Prof. Zhang is also the Visiting Professor in Siegen University, Germany, Cuiying Guest Professor (萃英讲席教授) in Lanzhou University, Guest Professors in National Chiao Tung University, Soochow University, Hefei University of Technology, Technical Institute of Physics and Chemistry (CAS), and Shenzhen Institute of Advanced Technology (CAS). Till now he has published over 340 peer-reviewed journal papers.

报告摘要

The outstanding properties of diamond make it an excellent material for various device applications. Recently, diamond-based electrochemical and biomedical sensors have attracted increasing research interests. It is known that the potential applications of materials depend not only on their intrinsic properties, but also on the surface geometries in which they appear. The extreme properties of diamond, however, make it difficult to be structured to a desired geometry. This presentation will review the recent progresses in growth and nano-/micro-structuring techniques of diamond, in particular a simple and applicable method developed by us to nanostructure diamond (ranging from microcrystalline to nanocrystalline) surfaces using bias-assisted reactive ion etching (RIE) in hydrogen/argon plasmas. Various diamond nanocone/nanopillar/ nanowhisker (nanowire) arrays with high uniformity and tunable density have been achieved by using this method. The effects of initial film structure, surface roughness and RIE conditions on the size, density and geometry of nanostructures are revealed. Surface nanostructuring of diamond films is demonstrated to be an effective approach to extend and/or enhance the properties of diamond with respect to its bulk and film counterparts. Example applications of the diamond nanostructures in field electron emission, electrode, and in situ probing and drug delivery at cell level are also discussed.

讲座信息

报告题目铂类抗癌药物的功能化和药物输送

报告人朱光宇 教授

邀请人蓝敏焕

时间2019年5月14日(周二)

上午11:00-12:00

地点中南大学新校区化学楼133多功能报告厅

主讲人简介

朱光宇(Guangyu Zhu)博士,香港城市大学化学系副教授(终身教职),博士生导师;香港城市大学深圳研究院研究员。2002年本科毕业于北京大学化学与分子工程学院,本科期间从事蛋白与配体相互作用的研究(导师:来鲁华教授)。同年赴美国匹兹堡大学(University of Pittsburgh)化学系与药学院攻读博士研究生学位(导师:Billy W. Day教授);2007年获得化学博士学位,期间从事抗癌药物的筛选和生物评测工作。2007 年至2011 年在美国麻省理工学院(MIT)化学系攻读博士后,从事铂类抗癌药物的研究(合作导师:Stephen J. Lippard 教授)。目前研究领域:新型抗癌药物的机制和发展,利用纳米药物载体提高抗癌药的生物活性,以及化学生物学。在铂类抗癌药物合成和作用机理方面掌握了一整套独到的研究技术。先后在Nat. Commun., PNAS, JACS, Angew. Chem. Int. Ed., Cancer Res., Adv. Healthcare Mater. 等国际一流杂志发表论文60余篇,并获得王宽诚教育基金会学者奖(2017)等多项荣誉。

报告摘要

Despite the broad clinical applications of platinum-based anticancer drugs including cisplatin, their side-effects and resistance issues have encouraged researchers to look for novel metal-based anticancer complexes. Non-traditional platinum compounds have been extensively studied and they hold the promise to be further developed as the next-generation platinum drugs. On the other hand, using nanomaterials to deliver cisplatin specifically into cancer cells has proven to be promising to increase the anticancer efficacy of cisplatin and has been a hot topic in the recent years. In this presentation, I will summarize the recent progress in my laboratory in 1) the design, synthesis, and biological evaluation of dual-targeting non-traditional platinum anticancer agents and 2) investigation on the action mechanism of metal-based anticancer agents. Examples of platinum constructs that promote the activation of p53 pathway and that have chemo-immunotherapy function will be given.

编辑:郑卉萍

审核:廖滟菁

责编:刘世宏

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